In vitro activity of nifuratel on vaginal bacteria: could it be a good candidate for the treatment of bacterial vaginosis?
نویسندگان
چکیده
Bacterial vaginosis is characterized by a shift of the physiological flora to a diverse spectrum of bacteria, where Gardnerella vaginalis and Atopobium vaginae are the most important markers. In this study, the antimicrobial activity of nifuratel against G. vaginalis, A. vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G. vaginalis and A. vaginae without affecting lactobacilli.
منابع مشابه
Bacterial Vaginosis, Atopobium vaginae and Nifuratel
As bacterial vaginosis (BV) is a potential cause of obstetric complications and gynecological disorders, there is substantial interest in establishing the most effective treatment. Standard treatment - metronidazole or clindamycin, by either vaginal or oral route � is followed by relapses in about 30% of cases, within a month from treatment completion. This inability to prevent recurrences refl...
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Background & Aim: Bacterial vaginosis is characterized by an imbalance in vaginal natural discharges due to an overgrowth of anaerobic bacteria as well as a concomitant decrease in the number of lactobacilli and increase in vaginal PH to more than 4.5. Bacterial vaginosis increases the risk of pelvic inflamatory disease, postoperative infection following hysterectomy, cervix abnormal cytology a...
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Abstract Introduction: Bacterial vaginosis (BV) is the most common cause of abnormal vaginal discharge in women during reproductive age. Diagnosis of bacterial vaginosis via clinical Amsel criteria remains widely competent. Objective: The aim of the study was to evaluate the effect of tinidazole tablets via Amsel criteria in Patients diagnosed Bacterial Vaginosis. Methods: In This rand...
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Background & Aims: Developing bacterial vaginosis is of high prevalence especially in pregnant women. The most common causes of bacterial vaginosis are anaerobic microorganisms such as Gardnerella vaginalis. The aim of this study was to determine the prevalence of Gardenerella vaginalis isolated in women with bacterial and non-bacterial vaginosis. Materials & Methods: The study was con...
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Bacterial vaginosis or non-specific vaginitis describes the disease caused by a change in the normal Flora of the vagina, which leads to the elimination of Lactobacilli, generating hydrogen peroxide and excess growth of bacteria, particularly anaerobic bacteria. This disease is the most prevalent infection of the female genital tract, and the rate of frequency of anaerobic bacteria, specificall...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 55 5 شماره
صفحات -
تاریخ انتشار 2011